A study in Cell Reports Medicine shows significantly lower NAD+ levels in the brains of Alzheimer’s patients, especially in the parietal and occipital regions.
The findings highlight a strong correlation between NAD+ depletion and mitochondrial dysfunction, reinforcing the role of redox metabolism in neurodegeneration. Authors suggest that NAD+ replenishment strategies (e.g. precursors or other interventions) should be explored as part of future treatment options for Alzheimer’s disease.
As NAD+ becomes a promising target for intervention, accurate and reliable measurement of NAD+ is more critical than ever.
Read the study here.
Research Links NAD+ Decline to Alzheimer’s Disease
