Emerging research highlights the critical role of NAD+/NADH and glutathione in ALS, linking them to key pathological processes such as hypermetabolism, glutamate excitotoxicity, mitochondrial dysfunction, oxidative stress, neuroinflammation, and DNA repair. | Nadmed Ltd | The standard of NAD measuring

REDOX Metabolites Key to ALS?

Emerging research highlights the critical role of NAD+/NADH and glutathione in ALS, linking them to key pathological processes such as hypermetabolism, glutamate excitotoxicity, mitochondrial dysfunction, oxidative stress, neuroinflammation, and DNA repair.

Download the white paper: REDOX-metabolites and ALS
Nicotinamide adenine dinucleotide (NAD+/NADH) and glutathione (GSH/GSSH) are two critical molecules involved in cellular redox balance and energy metabolism, regulating hundreds of metabolic processes, also playing a key role in neuroprotection. This white paper explores their role in ALS, underlying mechanisms, and therapeutic strategies targeting these pathways.

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NADMED, a spin-out from the University of Helsinki’s mitochondrial laboratory, has developed the first reliable and accurate method for measuring all six REDOX metabolites, including NADs, vital for energy production and cell repair, and glutathione, a crucial antioxidant combating oxidative stress.

In collaboration with pharmaceutical companies, NADMED is advancing research into treatments for neurodegenerative diseases like ALS. Early findings are highly promising, positioning REDOX metabolites at the forefront of new drug and therapy development.

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NADMED provides NAD testing kits for professional laboratories. Our blood kit is the only CE-marked option available, while our tissue and cell kits are offered as RUO. Explore also our laboratory services.

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Emerging research highlights the critical role of NAD+/NADH and glutathione in ALS, linking them to key pathological processes such as hypermetabolism, glutamate excitotoxicity, mitochondrial dysfunction, oxidative stress, neuroinflammation, and DNA repair. | Nadmed Ltd | The standard of NAD measuring
Emerging research highlights the critical role of NAD+/NADH and glutathione in ALS, linking them to key pathological processes such as hypermetabolism, glutamate excitotoxicity, mitochondrial dysfunction, oxidative stress, neuroinflammation, and DNA repair. | Nadmed Ltd | The standard of NAD measuring

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